Scarred Heart: A Case Series

Hydroxychloroquine Induced Retinopathy: A Case Series

Background and Purpose: Occular toxicity is one of the most important complications of Hydroxychloroquine. Not any type of treatment has so far been found and recommended for this disorder. The purpose of this study was to report some characteristics of patients with Hydroxychloroquine Induced Retinopathy.    Materials and Methods: From 107 patients with rheumatoid arthritis (...

Scarred by a death receptor

Catastrophe gradient drives anaphase B I t takes a polar catastrophe—oodles of them, actually—to get through anaphase, suggest Cheerambathur et al. on page 995. Their modeling reveals that concentrating microtubule catastrophes near the spindle poles might drive the second half of anaphase. Anaphase in fl y cells is a two-step process: fi rst the chromosomes migrate to the poles (anaphase A), t...

A Change of Heart: Case Series of Peripartum Cardiomyopathy

Peripartum cardiomyopathy (PPCM) is an uncommon disease of pregnancy, occurring in about 1 in 2000 live births, and is characterized by the development of heart failure, due to left ventricular systolic dysfunction. It is associated with high rates of maternal and neonatal mortality. Cardiac disease is the leading cause of maternal death in the UK: PPCM accounts for about 17% of these. Clinical...

A Heart-Wrenching Case of Loperamide Toxicity

Case Series Case Series

30 SAJR March 2013 Vol. 17 No. 1 Primary bone tumours account for 5% of all adolescent and child cancers. The Ewing’s sarcoma family of tumours is an aggressive form of childhood cancer and comprises the second most common primary bone tumour that includes Ewing’s sarcoma, Askin’s tumour and peripheral primitive neuro-ectodermal tumour (PNET). When Ewing’s sarcoma arises in soft tissue (25%) ra...